| Identification | Back Directory | [Name]
Nargenicin B1, CP 51467 | [CAS]
75923-01-2 | [Synonyms]
Nargenicin
Nocardia speluncae
Nocardia niigatensis
Nocardia inohamensis
Nocardia thailandica
Nargenicin B1, CP 51467
Nocardia . rhamnosiphila |
| Hazard Information | Back Directory | [Uses]
Nargenicin (CP-47,444) is a 10-membered macrocyclic lactone isolated from Nocardia in 1980 as an antibiotic. The macrocyclic lactone is anchored through vicinal carbons to a decalin bearing a pyrrole ester. Nargenicin exhibits potent activity against Gram positive bacteria, in particular MRSA strains. More recently, nargenicin has been shown to enhance retinoate-induced cell differentiation. |
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