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75969-83-4

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75969-83-4 Structure

75969-83-4 Structure
IdentificationBack Directory
[Name]

11-Hydroxycanthin-6-one
[CAS]

75969-83-4
[Synonyms]

11-Hydroxycanthin-6-one
CANTHIN-6-ONE, 11-HYDROXY-
6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 11-hydroxy-
[Molecular Formula]

C14H8N2O2
[MDL Number]

MFCD21333395
[MOL File]

75969-83-4.mol
[Molecular Weight]

236.23
Chemical PropertiesBack Directory
[Melting point ]

327-329 °C
[Boiling point ]

410.1±45.0 °C(Predicted)
[density ]

1.53±0.1 g/cm3(Predicted)
[pka]

8.62±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

11-Hydroxycanthin-6-one, a canthin-6-one (HY-N3536) alkaloid, is an antitumor agent which shows potent cytotoxic activity[1][2].
[Definition]

ChEBI: Amalorin is an organic heterotetracyclic compound and an alkaloid.
[References]

[1] Fukamiya N, et, al. Antitumor agents: LXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Med. 1987 Apr;53(2):140-3. DOI:10.1055/s-2006-962656
[2] Miyake K, et, al. Canthin-6-one alkaloids and a tirucallanoid from Eurycoma longifolia and their cytotoxic activity against a human HT-1080 fibrosarcoma cell line. Nat Prod Commun. 2010 Jan;5(1):17-22. PMID:20184012
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