| Identification | Back Directory | [Name]
2-PYRIMIDINEMETHANAMINE | [CAS]
75985-45-4 | [Synonyms]
RARECHEM AL BW 0784
2-PYRIMIDINEMETHANAMINE
PYRIMIDIN-2-YL-METHYLAMINE
1-pyrimidin-2-ylmethanamine
C-PYRIMIDIN-2-YL-METHYLAMINE
2-Pyrimidinemethanamine (9CI)
C-PyriMidin-2-yl-MethylaMine, fuMMerate
2-PYRIMIDINEMETHANAMINE ISO 9001：2015 REACH | [EINECS(EC#)]
804-700-4 | [Molecular Formula]
C5H7N3 | [MDL Number]
MFCD06212857 | [MOL File]
75985-45-4.mol | [Molecular Weight]
109.13 |
| Chemical Properties | Back Directory | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
Chloroform (Sparingly), Methanol (Slightly) | [form ]
Oil | [color ]
Pale Yellow to Dark Yellow |
| Hazard Information | Back Directory | [Chemical Properties]
white powder | [Uses]
2-Pyrimidinemethanamine can be prepared to combat abiotic plant stress. | [Synthesis]
General procedure for the synthesis of 2-methylaminopyrimidine from 2-cyanopyrimidine: To a stirred solution of 2-cyanopyrimidine (10) (0.2 g, 0.9 mmol) in ethanol (1 mL) was added 10% palladium/carbon (20 mg) under a nitrogen atmosphere. The reaction mixture was stirred under hydrogen atmosphere (using a balloon to maintain atmospheric pressure) for 12 h. Upon completion of the reaction, it was filtered through a diatomaceous earth pad. The filtrate was concentrated under reduced pressure to give the crude product. The crude product was purified by neutral alumina column chromatography (eluent: ethyl acetate/hexane = 1:1) to afford 2-methylaminopyrimidine (24) (0.19 g, 95% yield). Thin layer chromatography (TLC) conditions: 50% ethyl acetate/hexane (Rf: 0.1). 1H NMR (400 MHz, CDCl3): δ 8.70 (d, J=5.2 Hz, 2H), 7.16 (t, J=4.8 Hz, 1H), 4.19 (s, 1H), 4.11-4.08 (m, 1H). | [References]
[1] Patent: WO2013/13238, 2013, A2. Location in patent: Page/Page column 42
[2] Patent: WO2014/120783, 2014, A1. Location in patent: Paragraph 00143
[3] Patent: US5312823, 1994, A |
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