| Identification | Back Directory | [Name]
1-Dehydro-6-gingerdione | [CAS]
76060-35-0 | [Synonyms]
Dehydrogingerdione, 6-
1-Dehydro-6-gingerdione
(1E)-1-(4-Hydroxy-3-methoxyphenyl)-1-decene-3,5-dione
1-Decene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-, (1E)- | [Molecular Formula]
C17H22O4 | [MOL File]
76060-35-0.mol | [Molecular Weight]
290.35 |
| Chemical Properties | Back Directory | [Boiling point ]
448.9±40.0 °C(Predicted) | [density ]
1.105±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
8.69±0.46(Predicted) |
| Hazard Information | Back Directory | [Description]
1-Dehydro-6-gingerdione is 5-HT1A receptor partial agonists.
1-Dehydro-6-gingerdione has antioxidant and anti-inflammatory activities.
3. 1-Dehydro-6-gingerdione significantly suppresses the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) proteins in a concentration-dependent fashion. | [Uses]
6-Dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5[1]. | [Definition]
ChEBI: [6]-Dehydrogingerdione is a hydroxycinnamic acid. | [target]
PGE | NOS | COX | [References]
[1] Chung-Yi Chen, et al. 6-dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5. J Agric Food Chem. 2010 May 12;58(9):5604-11. DOI:10.1021/jf904260b |
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