| Identification | Back Directory | [Name]
GYKI 13324 | [CAS]
76123-41-6 | [Synonyms]
GYKI 13324
1-(2-chloroethyl)-3-[4-[2-chloroethylcarbamoyl(nitroso)amino]-2,3-dihydroxybutyl]-1-nitrosourea | [Molecular Formula]
C10H18Cl2N6O6 | [MOL File]
76123-41-6.mol | [Molecular Weight]
389.19 |
| Hazard Information | Back Directory | [Description]
GYKI-13324 is bifunctional nitrosoureido derivative and alkylating agent. GYKI-13324 was studied on human colorectal tumor xenograft lines. Given orally in single or multiple daily doses, GYKI-13324 produced long-term or total regression of adenomatous, but only marginal growth delay of mucinous tumors. GYKI-13324, with slightly lower toxicity than that of BCNU, seems to be a candidate in the clinical management of colorectal tumors. |
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