| Identification | Back Directory | [Name]
AH 21-132 | [CAS]
76166-55-7 | [Synonyms]
AH 21-132
Benzafentrine
Benafentrine dimaleate | [Molecular Formula]
C23H27N3O3.2C4H4O4 | [MDL Number]
MFCD00876412 | [MOL File]
76166-55-7.mol | [Molecular Weight]
625.628 |
| Hazard Information | Back Directory | [Description]
Benafentrine dimaleate is a phosphodiesterase (PDE) 3/4 inhibitors and platelet activating factor receptor (PAFR) antagonists potentially for the treatment asthma. | [Uses]
Benafentrine maleate is a platelet activating factor receptor (PAFR) antagonist and a PDE 4 inhibitor[1]. | [References]
[1] Kelly JJ, et al. Phosphodiesterase 4 in macrophages: relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitors. Biochem J. 1996 Sep 1;318 ( Pt 2)(Pt 2):425-36. DOI:10.1042/bj3180425 |
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