| Identification | Back Directory | [Name]
Piperidine, 4-(1H-pyrazol-1-yl)- (9CI) | [CAS]
762240-09-5 | [Synonyms]
4-(Pyrazol-1-yl)piperidine
4-(1H-pyrazol-1-yl)piperidine
Piperidine,4-(1H-pyrazol-1-yl)
4-(1H-pyrazole-1-yl)piperidine
Piperidine, 4-(1H-pyrazol-1-yl)- (9CI) | [Molecular Formula]
C8H13N3 | [MDL Number]
MFCD09998987 | [MOL File]
762240-09-5.mol | [Molecular Weight]
151.21 |
| Chemical Properties | Back Directory | [Boiling point ]
272.5±33.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [pka]
9.83±0.10(Predicted) | [Appearance]
White to light yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
Step C: Synthesis of 4-(1H-pyrazol-1-yl)piperidine (i-4)
The tert-butyl 4-(1H-pyrazol-1-yl)piperidine-1-carboxylate (50 mg, 0.2 mmol) obtained from Step B was dissolved in a dioxane solution (2.0 mL) of 4M HCl. The reaction mixture was stirred at room temperature for 1 hour. Subsequently, the solvent was removed by concentration under reduced pressure and dried under high vacuum to afford the white solid product 4-(1H-pyrazol-1-yl)piperidine (i-17) (30 mg, 96% yield). The product was analyzed by ESI-MS and the calculated value (C8H13N3) was 151.11 and the measured value was 151.11 [M+H]+, found to be 152.10. | [References]
[1] Patent: EP2632457, 2017, B1. Location in patent: Paragraph 0088; 0094
[2] Patent: WO2013/10453, 2013, A1. Location in patent: Page/Page column 95 |
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| Company Name: |
SynAsst Chemical.
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021-60343070 |
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www.chemicalbook.com/ShowSupplierProductsList15848/0_EN.htm |
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