ChemicalBook--->CAS DataBase List--->76265-48-0

76265-48-0

76265-48-0 Structure

76265-48-0 Structure
IdentificationBack Directory
[Name]

nodusmicin
[CAS]

76265-48-0
[Synonyms]

U 59761
nodusmicin
11,14b-Epoxy-14bH-naphth[2,1-e]oxecin-6(7H)-one, 3,4,8,8a,10a,11,12,13,14,14a-decahydro-12,14-dihydroxy-4-[(1R)-1-hydroxyethyl]-7-methoxy-1,3,13-trimethyl-, (1E,3R,4S,7S,8aS,10aR,11R,12R,13R,14R,14aS,14bS)- (9CI)
[Molecular Formula]

C23H34O7
[MDL Number]

MFCD28898540
[MOL File]

76265-48-0.mol
[Molecular Weight]

422.51
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: soluble; DMSO: soluble; Ethanol: soluble
[form ]

A solid
Hazard InformationBack Directory
[Description]

Nodusmicin is a macrolide antibiotic. It has activity against antibiotic-susceptible and -resistant S. aureus with MIC values of 125, 250, and 250 μg/ml for UC-76, UC-6685, and UC-6690 strains, respectively.
[Uses]

Nodusmicin is a co-metabolite of nargenicin, bearing the core macrocyclic lactone but lacking the pyrrole ester. Like nargenicin, nodusmicin is a potent antibiotic active against both aerobic and anaerobic bacteria. Lack of availability has restricted a more extensive investigation of nodusmicin.
[Uses]

Nodusmicin is a potent antibiotic against aerobic and anaerobic bacteria.
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