ChemicalBook--->CAS DataBase List--->76275-67-7

76275-67-7

76275-67-7 Structure

76275-67-7 Structure
IdentificationBack Directory
[Name]

rac-7-hydroxy Propranolol (hydrochloride)
[CAS]

76275-67-7
[Synonyms]

7-Hydroxy Propranolol HCl
7-Hydroxypropranolol hydrochloride
rac-7-hydroxy Propranolol (hydrochloride)
8-(2-Hydroxy-3-(isopropylamino)propoxy)naphthalen-2-ol hydrochloride
[Molecular Formula]

C16H22ClNO3
[MDL Number]

MFCD32661440
[MOL File]

76275-67-7.mol
[Molecular Weight]

311.804
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: soluble
[form ]

A solid
Hazard InformationBack Directory
[Description]

rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of (±)-propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol).1 It also demonstrates potent vasodilator activity (0.20 potency relative to propranolol; pA2 = 7.58).
[References]

1. Oatis, J.E., Jr., Russell, M.P., Knapp, D.R., et al. Ring-hydroxylated propranolol: Synthesis and β-receptor antagonist and vasodilating activities of the seven isomers J. Med. Chem. 24(3),309-314(1981).
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