| Identification | Back Directory | [Name]
6,7-dimethoxy-N-(4-nitrophenyl)quinazolin-4-amine | [CAS]
765899-28-3 | [Synonyms]
WHI-1
UL 97-Kinase-IN-1
6,7-dimethoxy-N-(4-nitrophenyl)quinazoli
6,7-dimethoxy-N-(4-nitrophenyl)quinazolin-4-amine
4-Quinazolinamine, 6,7-dimethoxy-N-(4-nitrophenyl)-
6,7 dimethoxy N (4 nitrophenyl)quinazoli,6,7dimethoxyN(4nitrophenyl)quinazoli | [Molecular Formula]
C16H14N4O4 | [MDL Number]
MFCD29035147 | [MOL File]
765899-28-3.mol | [Molecular Weight]
326.31 |
| Hazard Information | Back Directory | [Uses]
BCRP-IN-1 (compound 48) is a potent inhibitor of breast cancer resistance protein (BCRP), with IC50s of 2.92 μM and 2.46 μM in Hoechst 33342 assay and Pheophorbide A assay, respectively[1]. | [References]
[1] "Kapil Juvale, et al. Investigation of quinazolines as inhibitors of breast cancer resistance
protein (ABCG2). Bioorg Med Chem. 2013 Dec 15;21(24):7858-73. " DOI:10.1016/j.bmc.2013.10.007 |
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