| Identification | Back Directory | [Name]
6-Bromopurine | [CAS]
767-69-1 | [Synonyms]
Bb-127e
Nsc 45150
6-bromo-purin
6-BROMOPURINE
Einecs 212-187-8
Purine, 6-bromo-
6-Bromo-7H-purine
6-Bromo-9H-purine
6-bromo-1H-purine
6-Bromopurine ,98%
9H-Purine, 6-bromo-
1H-Purine, 6-bromo- (9ci)
6-bromo-9H-purine(SALTDATA: FREE) | [EINECS(EC#)]
212-187-8 | [Molecular Formula]
C5H3BrN4 | [MDL Number]
MFCD00022648 | [MOL File]
767-69-1.mol | [Molecular Weight]
199.01 |
| Chemical Properties | Back Directory | [Melting point ]
>300 °C (lit.) | [Boiling point ]
240.9±50.0 °C(Predicted) | [density ]
2.28±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
7.39±0.20(Predicted) | [color ]
Pale Beige | [InChI]
InChI=1S/C5H3BrN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10) | [InChIKey]
CTGFGRDVWBZYNB-UHFFFAOYSA-N | [SMILES]
N1C2C(=NC=NC=2Br)NC=1 |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [WGK Germany ]
3
| [RTECS ]
UO7513000
| [HS Code ]
29339900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Description]
6-Bromopurine is a 6-halogenated purine nucleoside analogue. Studies have shown that 6-halogenopurine inhibits tumour growth when combined with azaserine, which may be related to the blockage of guanine nucleotide biosynthesis. The inhibitory effect of bromopurine occurs between inosine 5‘-phosphate and guanosine 5’-phosphate. 6-Bromopurine also enhances the carcinostatic activity of azaserine. In addition, 6-Bromopurine is also used as an intermediate in the synthesis of Idelalisib. | [Chemical Properties]
Dark yellow crystalline powder | [Uses]
6-Bromopurine was used in the synthesis of 6-halopurine alkynes and corresponding triazole derivatives. 6-Bromopurine was used in the synthesis and chemical characterization of 2,3,4,5-tetrahydro-1,5-benzoxazepines-3-ol. | [General Description]
6-Bromopurine enhances the carcinostatic activity of azaserine in a test system employing ascites cell forms of sarcoma 180 and Ehrlich carcinoma in vivo. 6-bromopurine nucleosides are excellent substrates for substitution reactions with N-, O-, and S-containing nucleophiles in polar solvents. |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
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