| Identification | Back Directory | [Name]
Piperazine, 1-[(1S)-1-(4-fluorophenyl)-2-[4-[4-(2-methoxy-1-naphthalenyl)butyl]-1-piperazinyl]ethyl]hexahydro-4-(1-methylethyl)- | [CAS]
768357-45-5 | [Synonyms]
MCL0129
MCL-0129
MCL 0129
Piperazine, 1-[(1S)-1-(4-fluorophenyl)-2-[4-[4-(2-methoxy-1-naphthalenyl)butyl]-1-piperazinyl]ethyl]hexahydro-4-(1-methylethyl)- | [Molecular Formula]
C34H47FN4O | [MOL File]
768357-45-5.mol | [Molecular Weight]
546.78 |
| Hazard Information | Back Directory | [Uses]
MCL-0129 is a compound with anxiolytic and antidepressant activity and is a selective MC4 receptor antagonist that exhibits anxiolytic and antidepressant-like behaviors in multiple rodent models. | [References]
[1] Anxiolytic-like and antidepressant-like activities of MCL0129 (1-[(S)-2-(4-fluorophenyl)-2-(4-isopropylpiperadin-1-yl)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine), a novel and potent nonpeptide antagonist of the melanocortin-4 receptor DOI:10.1124/jpet.102.044826 |
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