| Identification | Back Directory | [Name]
FLUORESCEIN-5-THIOSEMICARBAZIDE | [CAS]
76863-28-0 | [Synonyms]
5-FTSC
FLUORESCEIN-5-THIOSEMICARBAZIDE
Fluorescein-5-thiosemicarbazide HCl
FLUORESCEIN-5-THIOSEMICARBAZIDE [5-FTSC]
Fluorescein-5-thiosemicarbazide Hydrochloride
FLUORESCEIN-5-THIOSEMICARBAZIDE, FOR FLU ORESCENCE
Hydrazinecarbothioamide, N-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)- | [Molecular Formula]
C21H15N3O5S | [MDL Number]
MFCD04221432 | [MOL File]
76863-28-0.mol | [Molecular Weight]
421.43 |
| Chemical Properties | Back Directory | [Boiling point ]
723.8±70.0 °C(Predicted) | [density ]
1.70±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMF: soluble | [form ]
Solid | [pka]
9.33 ± 0.20, most acidic, temperature:
25 °C; 1.76 ± 0.19, most basic(at 25℃) | [color ]
Yellow solid | [Appearance]
Solid Powder | [λmax]
492 nm (Buffer pH 9.0) | [Biological Applications]
Analyzing
low-molecular mass aldehydes in urine, drinking
waters; assaying glycosaminoglycan-degrading enzyme
activity; detecting sterols; measuring/quantifying
degree of hair damage | [Major Application]
Characterizing soft material
interfaces; understanding fibrous network structures; in
nanodevice preparation; functionalizing/ encapsulatiing
particles by initiated chemical vapor deposition
(iCVD); functional polymer coatings; high
refractive index coatings; papers
| [InChI]
InChI=1S/C21H15N3O5S/c22-24-20(30)23-10-1-4-14-13(7-10)19(27)29-21(14)15-5-2-11(25)8-17(15)28-18-9-12(26)3-6-16(18)21/h1-9,25-26H,22H2,(H2,23,24,30) | [InChIKey]
OIMMDIXLTJAVTF-UHFFFAOYSA-N | [SMILES]
N(C(NC1C=CC2C3(C4=C(C=C(O)C=C4)OC4=C3C=CC(O)=C4)OC(=O)C=2C=1)=S)N |
| Hazard Information | Back Directory | [Description]
Fluorescein-5-thiosemicarbazide (FTSC) is a fluorescent probe for labeling aldehydes and ketones in cell surface. | [Uses]
Fluorescein-5-thiosemicarbazide can be used for Sox2 transcription factor binds RNA. | [Uses]
Labeling of cell-surface functional groups (glycophorins). Detection of protein carbonyls in aging tissues. |
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