| Identification | Back Directory | [Name]
Begacestat | [CAS]
769169-27-9 | [Synonyms]
GSI-953
Begacestat
Begacestat(GSI-953)
GSI-953
DISCONTINUED
Begacestat (Synonyms: GSI-953)
5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxyMethyl)-2-(trifluoroMethyl)propyl]-2-thiophenesulfonaMide
5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2- (trifluoromethyl)propyl] thiophene-2-sulfonamide
2-Thiophenesulfonamide, 5-chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2-(trifluoromethyl)propyl]-
(2S)-S-(5-chlorothiophen-2-yl)-4,4,4-trifluoro-1-hydroxy-N-Methyl-3-(trifluoroMethyl)butane-2-sulfonaMido | [Molecular Formula]
C9H8ClF6NO3S2 | [MDL Number]
MFCD18782675 | [MOL File]
769169-27-9.mol | [Molecular Weight]
391.74 |
| Chemical Properties | Back Directory | [Boiling point ]
355℃ | [density ]
1.642 | [Fp ]
169℃ | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥15mg/mL | [form ]
powder | [pka]
8.16±0.50(Predicted) | [color ]
white to tan |
| Hazard Information | Back Directory | [Uses]
Begacestat (GSI-953) is a selective β-secretase inhibitor that selectively inhibits cleavage of APP over Notch. GSI-953 is used for treating diseases such as cancer in relation to prevention of intestinal secretory metaplasia. |
|
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
http://www.weikeqi-biotech.com/ |
|