| Identification | Back Directory | [Name]
hexahydro-3a,7a-dimethyl-4,7-epoxy-1H-isoindole-1,3(2H)-dione | [CAS]
76970-77-9 | [Synonyms]
Cantharidin imide
hexahydro-3a,7a-dimethyl-4,7-epoxy-1H-isoindole-1,3(2H)-dione
4,7-Epoxy-1H-isoindole-1,3(2H)-dione, hexahydro-3A,7A-dimethyl-, (3aalpha,4beta,7beta,7aalpha)- | [Molecular Formula]
C10H13NO3 | [MOL File]
76970-77-9.mol | [Molecular Weight]
195.22 |
| Chemical Properties | Back Directory | [Melting point ]
205-206 °C(Solvent: Ethanol) | [Boiling point ]
353.647±35.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.310±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
11.185±0.60(predicted) |
| Hazard Information | Back Directory | [Description]
Cantharidin imide is a PP1/2A inhibitor found in Canarthis vesicatoria. It inhibits proliferation of colorectal cancer cells, increases MCP-1, IL-6, and IL-β levels, and inhibits differentiation and resorptive activity of osteoclasts. This compound can produce severe skin inflammation, and is extremely toxic if ingested orally. |
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