77086-19-2

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77086-19-2 Structure

Identification	Back Directory
[Name] (+)-MK 801 MALEATE
[CAS] 77086-19-2
[Synonyms] ()-MK-801 (-)-MK 801 MALEATE (+)-MK 801 MALEATE DIZOCILPINE MALEATE (+)-MK-801 HYDROGEN MALEATE (-)-MK 801 hydrogen maleate 5,10-Imino-5H-dibenzo[a,d]cycloheptene, 10,11-dihydro-5-methyl-,(5R,10S)- (5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cylcohepten-5,10-iminemaleate (5R,10S)-(-)-5-METHYL-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5,10-IMINE MALEATE (5R,10S)-(+)-5-METHYL-10,11-DIHYDRO-5H-DIBENZO[A,D]-CYCLOHEPTEN-5-10-IMINE, MALEATE (5R,10S)-(-)-5-Methyl-10,11-dihydro-(5H)-dibenzo[a.d]cylcoheptene-5,10-iminemaleate (5R,10S)-(+)-5-METHYL-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5,10-IMINE HYDROGEN MALEATE (5s,10r)-(-)-5-methyl-10,11-dihydro-5h-dibenzo-[a,d]-cyclo-hepten-5,10-imine hydrogen maleate
[Molecular Formula] C16H15N
[MDL Number] MFCD00082466
[MOL File] 77086-19-2.mol
[Molecular Weight] 221.3

Chemical Properties	Back Directory
[Melting point ] 68.5-69.5°
[alpha ] 589 -160.8° (c = 0.032 g/2 ml ethanol)
[storage temp. ] room temp
[solubility ] DMSO: >20mg/mL
[form ] solid
[color ] white
[optical activity] [α]25/D 117.7°, c = 1 in methanol(lit.)

Safety Data	Back Directory
[WGK Germany ] 3

Hazard Information	Back Directory
[Uses] Biochemical probe for NMDA receptors.
[General Description] (-)-MK-801 hydrogen maleate is a less potent stereoisomer of (+)-MK-801.
[Biological Activity] Less active enantiomer (10-fold less potent in behavioral studies) than (+)-MK 801 maleate ((5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate ).
[Biochem/physiol Actions] Less active enantiomer of (+)-MK-801 hydrogen maleate

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