| Identification | Back Directory | [Name]
Dizocilpine | [CAS]
77086-21-6 | [Synonyms]
C13737
Dizocilpine
MK-801 (Dizocilpine)
Dizocilpine USP/EP/BP
Dizocilpine free base(MK801)
(5S)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5α,10α-imine
[5S,10R,(+)]-10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine
5H-Dibenzo[a,d]cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S,10R)-
[5S,10R,(+)]-10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5α,10α-imine | [Molecular Formula]
C16H15N | [MDL Number]
MFCD06412575 | [MOL File]
77086-21-6.mol | [Molecular Weight]
221.3 |
| Hazard Information | Back Directory | [Uses]
Neuroprotective. | [Definition]
ChEBI: Dizocilpine is an organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory. It has a role as a NMDA receptor antagonist, an anaesthetic, an anticonvulsant, a nicotinic antagonist and a neuroprotective agent. It is a secondary amino compound and a tetracyclic antidepressant. It is a conjugate base of a dizocilpine(1+). |
|
|