| Identification | Back Directory | [Name]
8-Acetyloxy-5,6,7,8-tetrahydro-2,3,13-trimethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-1-ol | [CAS]
77174-33-5 | [Synonyms]
Norkadsurin
Acetylbinankadsurin A
8-Acetyloxy-5,6,7,8-tetrahydro-2,3,13-trimethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-1-ol
Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxole-1,8-diol, 5,6,7,8-tetrahydro-2,3,13-trimethoxy-6,7-dimethyl-, 8-acetate, (6R,7R,8R,13aS)- | [Molecular Formula]
C24H28O8 | [MOL File]
77174-33-5.mol | [Molecular Weight]
444.47 |
| Chemical Properties | Back Directory | [Boiling point ]
590.464±50.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.319±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
8.809±0.70(predicted) |
| Hazard Information | Back Directory | [Uses]
Acetyl-binankadsurin A (compound 5) is a lignan isolated from Kadsura longipedunculata. Acetyl-binankadsurin A has low inhibitory activity against HIV-1 protease, with IC50 >100 μg/mL[1]. | [References]
[1] Sun QZ, et al. Three new lignans, longipedunins A-C, from Kadsura longipedunculata and their inhibitory activity against HIV-1 protease. Chem Pharm Bull (Tokyo). 2006 Jan;54(1):129-32. DOI:10.1248/cpb.54.129 |
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