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7722-44-3

7722-44-3 Structure

7722-44-3 Structure
IdentificationBack Directory
[Name]

N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-)
[CAS]

7722-44-3
[Synonyms]

Colistin A
Polymyxin E1
XQKABMNFUQVRFN-SADGAIANSA-N
Colistin A-d5 Discontinued
N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-)
N2-(6-Methyl-1-oxooctyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-)
[Molecular Formula]

C53H100N16O13
[Molecular Weight]

1169.46
Chemical PropertiesBack Directory
[alpha ]

225461 -93.3° (2% acetic acid)
[Boiling point ]

1536.8±65.0 °C(Predicted)
[density ]

1.25±0.1 g/cm3(Predicted)
[pka]

13.08±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Colistin A is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria.
[Definition]

ChEBI: A polymyxin having a (6R)-6-methyloctanoyl group at the amino terminus.
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