| Identification | Back Directory | [Name]
3-(Aminocarbonyl)-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-pyridinium Triflate | [CAS]
774599-53-0 | [Synonyms]
3-(Aminocarbonyl)-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-pyridinium Triflate | [Molecular Formula]
C18H21F3N2O11S | [MOL File]
774599-53-0.mol | [Molecular Weight]
530.42 |
| Hazard Information | Back Directory | [Uses]
3-(Aminocarbonyl)-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-pyridinium Triflate is an intermediate in synthesizing β-Nicotinamide Mononucleotide (N407765), a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. |
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