| Identification | Back Directory | [Name]
Benzoic acid, 2-broMo-6-(broMoMethyl)-, Methyl ester | [CAS]
777859-74-2 | [Synonyms]
777859-74-2
ethyl 2-bromo-6-(bromomethyl)benzoate
METHYL 2-BROMO-6-(BROMOMETHYL)BENZOATE
2-Bromo-6-bromomethyl-benzoic acid methyl ester
Benzoic acid, 2-broMo-6-(broMoMethyl)-, Methyl ester | [Molecular Formula]
C9H8Br2O2 | [MDL Number]
MFCD18205380 | [MOL File]
777859-74-2.mol | [Molecular Weight]
307.967 |
| Questions And Answer | Back Directory | [Application]
Methyl 2-bromo-6-bromomethylbenzoate can be used as a pharmaceutical intermediate in the synthesis of other compounds with certain activities. An example of its application is as follows: A mixture of methyl 2-bromo-6-bromomethylbenzoate (0.71 mmol) and 4-methoxy-3-[2-(4-methylpiperidin-1-yl)-ethoxy]-aniline hydrochloride (1.5 equivalents) in anhydrous DMF (2 ml) was heated to 150°C for 10 minutes in a microwave reactor. The mixture was then concentrated under vacuum, and the residue was subjected to column chromatography, subsequently converted to hydrochloride, yielding a new compound with pharmacological activity, which can be used to treat CNS and other diseases. |
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