| Identification | Back Directory | [Name]
Milbemycin D | [CAS]
77855-81-3 | [Synonyms]
B-41D
Milbemycin D
MilbeMycin MIL
Antibiotic B-41D
Milbemycin D (~90%)
Milbemycin EP Impurity C
Milbemycin Impurity 3(Milbemycin EP Impurity C)
(6r,25)-5-o-demethyl-28-deoxy-6,28-epoxy-25-(1-methylethyl)m...
(6r,25)-5-o-demethyl-28-deoxy-6,28-epoxy-25-(1-methylethyl)milbemycin b
(6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-(1-methylethyl)milbemycin B
Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-25-(1-methylethyl)-, (6R,25R)- | [Molecular Formula]
C33H48O7 | [MOL File]
77855-81-3.mol | [Molecular Weight]
556.735 |
| Chemical Properties | Back Directory | [Melting point ]
186-188° | [alpha ]
D27 +107° (c = 0.25 in acetone) | [Boiling point ]
460.61°C (rough estimate) | [density ]
1.0367 (rough estimate) | [refractive index ]
1.5300 (estimate) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin D is a minor member of a group of analogues containing a 25-isopropyl substituent. Milbemycin D is a highly selective and potent nematocide and insecticide. Like the closely related avermectin, milbemycins are thought to act by opening glutamate sensitive chloride channels. | [Uses]
Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin D is a minor member of a group of analogues containing a 25-isopropyl substituent. Milbemycin D is a highly selective and potent nematocide and insecticide. Like the closely related avermectin, milbemycins are thought to act on chloride-gated ion channels. | [Definition]
ChEBI: Milbemycin D is a milbemycin originally isolated from Streptomyces hygroscopicus with formula C33H48O7 that has insecticidal and anthelmintic proerties. It has a role as an insecticide, an anthelminthic drug and a nematicide. |
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