| Identification | Back Directory | [Name]
DC-38-V | [CAS]
77879-90-4 | [Synonyms]
DC-38-V
NSC 338943
NSC 348115
Gilvocacin V
gilvocarcin V
AnandiMycin A, ToroMycin, 1072B
4-(6-Deoxy-α-D-galactofuranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one
4-(6-Deoxy-alpha-D-galactofuranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one
4-[(2R,3R,4R,5S)-3,4-dihydroxy-5-[(1R)-1-hydroxyethyl]oxolan-2-yl]-8-ethenyl-1-hydroxy-10,12-dimethoxynaphtho[1,2-c]isochromen-6-one | [Molecular Formula]
C27H26O9 | [MOL File]
77879-90-4.mol | [Molecular Weight]
494.493 |
| Chemical Properties | Back Directory | [Melting point ]
265.5°C | [Boiling point ]
507.55°C (rough estimate) | [density ]
1.2522 (rough estimate) | [refractive index ]
1.5500 (estimate) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
A film | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
Gilvocarcin V is a metabolite that displays potent antibacterial, antifungal and antiviral activity. | [Uses]
Gilvocarcin V is the major analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin V contains a vinyl group in the 8-position, and is the most potent analogue of the complex. It is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. The metabolite displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research suggests that the gilvocarcins act as photoactivated cross-linkers of DNA to histones. | [Uses]
Gilvocarcin V is the major analogue of a complex of C-glycoside antitumour actives isolated from a Streptomyces sp.. Gilvocarcin V contains a vinyl group in the 8-position, and is the most potent analogue of the complex. It is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. The metabolite displays potent antibacterial, antifungal, antiviral and antitumour activity. Recent research suggests that the gilvocarcins act as photoactivated crosslinkers of DNA to histones. | [storage]
+4°C |
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