| Identification | Back Directory | [Name]
auramycin B | [CAS]
78173-91-8 | [Synonyms]
auramycin B
1-Naphthacenecarboxylic acid, 4-[[[2''',3''-anhydro]-O-3,6-dideoxy-α-L-erythro-hexopyranos-4-ulos-1-yl-(1→4)-O-2,6-dideoxy-α-L-lyxo-hexopyranosyl-(1→4)-2,3,6-trideoxy-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-2-methyl-6,11-dioxo-, methyl ester, (1R,2R,4S)-... | [Molecular Formula]
C41H49NO15 | [MDL Number]
MFCD01713242 | [MOL File]
78173-91-8.mol | [Molecular Weight]
795.83 |
| Chemical Properties | Back Directory | [Melting point ]
161°C | [Boiling point ]
748.77°C (rough estimate) | [density ]
1.2495 (rough estimate) | [refractive index ]
1.6220 (estimate) | [pka]
6.41±0.70(Predicted) | [color ]
Yellow powder |
| Hazard Information | Back Directory | [Uses]
Auramycin B, an anthracycline antibiotic that shows marked antibacterial activity against Gram-positive bacteria. Auramycin B also exhibits antitumor activity against P388 and L1210 leukemia in mice[1]. | [Safety Profile]
Poison by intraperitoneal route.Mutation data reported. When heated to decomposition itemits toxic fumes of NOx. | [References]
[1] Fujiwara A, et al. New anthracycline antibiotics, auramycins and sulfurmycins. I. Isolation and characterization of auramycins A and B, and sulfurmycins A and B. J Antibiot (Tokyo). 1982 Feb;35(2):164-75. DOI:10.7164/antibiotics.35.164 |
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