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78263-90-8

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78263-90-8 Structure

78263-90-8 Structure
IdentificationBack Directory
[Name]

2-METHYL-5-HYDROXYTRYPTAMINE
[CAS]

78263-90-8
[Synonyms]

α-CH3-5-HT
α-Methyl-5-HT
2-methyl-5-HT
Methylserotonin
2-Methylserotonin
2-METHYL-5-HYDROXYTRYPTAMINE
2-Methyl-5-hydroxytryptaminHCl
3-(2-Aminopropyl)-1H-indol-5-ol
2-Methylserotonin Hydrochloride
2-METHYL-5-HYDROXYTRYPTAMINE USP/EP/BP
2-Methyl-3-(2-aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)-2-methyl-1H-indol-5-ol
5-Hydroxy-α-methyl-1H-indole-3-ethanamine
1H-Indol-5-ol, 3-(2-aminoethyl)-2-methyl-
1H-Indol-5-ol,3-(2-aMinoethyl)-2-Methyl-(NP3308)
[Molecular Formula]

C11H14N2O
[MDL Number]

MFCD00152134
[MOL File]

78263-90-8.mol
[Molecular Weight]

190.24
Chemical PropertiesBack Directory
[Boiling point ]

420.9±40.0 °C(Predicted)
[density ]

1.242±0.06 g/cm3(Predicted)
[RTECS ]

NM2565000
[storage temp. ]

Keep in dark place,Inert atmosphere,2-8°C
[solubility ]

H2O: 4.5 mg/mL
[form ]

solid
[pka]

10.17±0.40(Predicted)
[color ]

tan
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
[Signal word ]

Warning
[Hazard statements ]

H411-H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

2-Methylserotonin is a tryptamine derivative closely related to the neurotransmitter serotonin (S274980) which is a monoamine neurotransmitter, and acts as a moderately selective full agonist at the 5-HT3 receptor.
[Definition]

ChEBI: 2-methylserotonin is a member of tryptamines. It has a role as a serotonergic agonist. It is functionally related to a serotonin.
[in vivo]

2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) significantly decreases time of immobility thus showing anti-depressive-like effects[1].

Animal Model:Male Sprague-Dawley rats[1]
Dosage:3 mg/kg
Administration:I.p.; 45 minutes
Result:Significantly decreased time of immobility thus showing anti-depressive-like effects.
[IC 50]

5-HT3 Receptor
Spectrum DetailBack Directory
[Spectrum Detail]

2-METHYL-5-HYDROXYTRYPTAMINE(78263-90-8)1HNMR
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