| Identification | Back Directory | [Name]
2-METHYL-5-HYDROXYTRYPTAMINE | [CAS]
78263-90-8 | [Synonyms]
α-CH3-5-HT
α-Methyl-5-HT
2-methyl-5-HT
Methylserotonin
2-Methylserotonin
2-METHYL-5-HYDROXYTRYPTAMINE
2-Methyl-5-hydroxytryptaminHCl
3-(2-Aminopropyl)-1H-indol-5-ol
2-Methylserotonin Hydrochloride
2-METHYL-5-HYDROXYTRYPTAMINE USP/EP/BP
2-Methyl-3-(2-aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)-2-methyl-1H-indol-5-ol
5-Hydroxy-α-methyl-1H-indole-3-ethanamine
1H-Indol-5-ol, 3-(2-aminoethyl)-2-methyl-
1H-Indol-5-ol,3-(2-aMinoethyl)-2-Methyl-(NP3308) | [Molecular Formula]
C11H14N2O | [MDL Number]
MFCD00152134 | [MOL File]
78263-90-8.mol | [Molecular Weight]
190.24 |
| Chemical Properties | Back Directory | [Boiling point ]
420.9±40.0 °C(Predicted) | [density ]
1.242±0.06 g/cm3(Predicted) | [RTECS ]
NM2565000 | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
H2O: 4.5 mg/mL
| [form ]
solid
| [pka]
10.17±0.40(Predicted) | [color ]
tan
|
| Hazard Information | Back Directory | [Uses]
2-Methylserotonin is a tryptamine derivative closely related to the neurotransmitter serotonin (S274980) which is a monoamine neurotransmitter, and acts as a moderately selective full agonist at the 5-HT3 receptor. | [Definition]
ChEBI: 2-methylserotonin is a member of tryptamines. It has a role as a serotonergic agonist. It is functionally related to a serotonin. | [in vivo]
2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) significantly decreases time of immobility thus showing anti-depressive-like effects[1]. | Animal Model: | Male Sprague-Dawley rats[1] | | Dosage: | 3 mg/kg | | Administration: | I.p.; 45 minutes | | Result: | Significantly decreased time of immobility thus showing anti-depressive-like effects.
|
| [IC 50]
5-HT3 Receptor |
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