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78310-77-7

78310-77-7 Structure

78310-77-7 Structure
IdentificationBack Directory
[Name]

Thymus factor x
[CAS]

78310-77-7
[Synonyms]

TFX-Jelfa
Thymus factor x
[MDL Number]

MFCD01868670
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Thymic factor X (TFX-Jelfa) is an aqueous extract from juvenile calf thymuses and a natural stimulator of lymphocyte function[1][2].
[in vivo]

The percentage of necrotic lymphocytes in the spleen in Group I (infected with T. spiralis and treated with Thymus factor X (TFX)) is significantly lower than in the control group on day 7, and approximately the same as in the control group for the rest of the experiment. The percentage of necrotic lymphocytes in muscle tissue in Group I is approximately the same as in the control group on day 7, significantly lower on days 14 and 21 (p<0.0002), approximately the same on days 28 and 35, significantly lower on day 42, and significantly higher on day 60 (p<0.005)[1].

[References]

[1] Piekarska J, et al. Trichinella spiralis: Effect of thymus factor X on apoptosis and necrosis in mice. Exp Parasitol. 2009 Oct;123(2):128-33. DOI:10.1016/j.exppara.2009.06.009
[2] Skotnicki AB. Therapeutic application of calf thymus extract (TFX). Med Oncol Tumor Pharmacother. 1989;6(1):31-43. DOI:10.1007/BF02985221
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