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78441-82-4

78441-82-4 Structure

78441-82-4 Structure
IdentificationBack Directory
[Name]

N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide
[CAS]

78441-82-4
[Synonyms]

BMY-25271
N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide
1,2,5-Thiadiazole-3,4-diamine, N3-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-, 1-oxide
[Molecular Formula]

C12H19N5O2S2
[MDL Number]

MFCD30533313
[MOL File]

78441-82-4.mol
[Molecular Weight]

329.44
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Biological Activity]

BMY-25271 is a histamine H2 receptor antagonist.
[in vivo]

BMY-25271 is a histamine H2 receptor antagonist. The dose response curves are parallel and oral ED 50 values derived from probit analysis are 0.093, 0.97 and 6.9 mg/kg for BMY- 25271, ranitidine and cimetidine, respectively. Therefore it is about 10 and 74 times more potent than ranitidine and cimetidine, respectively.
[target]

Histamine H2 receptor

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