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785708-33-0

785708-33-0 Structure

785708-33-0 Structure
IdentificationBack Directory
[Name]

Photoregulin3 >=98% (HPLC)
[CAS]

785708-33-0
[Synonyms]

Photoregulin3
APA modulator T4
Photoregulin3 >=98% (HPLC)
[Molecular Formula]

C22H23N3O3
[MDL Number]

MFCD31699852
[MOL File]

785708-33-0.mol
[Molecular Weight]

377.44
Chemical PropertiesBack Directory
[Boiling point ]

563.0±60.0 °C(Predicted)
[density ]

1.25±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Soluble to 2 mM in DMSO
[form ]

powder
[pka]

5.05±0.40(Predicted)
[color ]

white to beige
Hazard InformationBack Directory
[Description]

Photoregulin3 is a inhibitor of rod photoreceptor gene expression, potentially though Nr2e3 modulation.
[Uses]

Photoregulin 3 (compound T4) can promote distal-to-proximal alternative polyadenylation (APA) activity in multiple transcripts[1].
[storage]

Store at -20°C
[References]

[1] Shinsuke Araki, et al. Decoding Transcriptome Dynamics of Genome-Encoded Polyadenylation and Autoregulation with Small-Molecule Modulators of Alternative Polyadenylation. Cell Chem Biol. 2018 Dec 20;25(12):1470-1484.e5. DOI:10.1016/j.chembiol.2018.09.006
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