ChemicalBook--->CAS DataBase List--->78582-17-9

78582-17-9

78582-17-9 Structure

78582-17-9 Structure
IdentificationBack Directory
[Name]

3-DEAZA-2'-DEOXYADENOSINE
[CAS]

78582-17-9
[Synonyms]

Aids002055
Aids-002055
3-Deaza-2'-da
3-DEAZA-2'-DEOXYADENOSINE
1H-Imidazo[4,5-c]pyridin-4-amine, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-
1H-Imidazo[4,5-C]pyridin-4-amine, 1-(2'-deoxy-.beta.-D-erythro-pentofuranosyl)-
[Molecular Formula]

C11H14N4O3
[MDL Number]

MFCD08062098
[MOL File]

78582-17-9.mol
[Molecular Weight]

250.25
Chemical PropertiesBack Directory
[Melting point ]

208-209 °C
[Boiling point ]

617.7±65.0 °C(Predicted)
[density ]

1.75±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 5 mg/ml; DMSO: 20 mg/ml; PBS (pH 7.2): 10 mg/ml
[form ]

A crystalline solid
[pka]

13.88±0.60(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

3-Deaza-2 '-deoxyadenosine is a nucleoside analog synthesized from 2' -deoxyadenosine. 3-Deaza-2 '-deoxyadenosine inhibits RNA synthesis by binding to ribose fragments of ribonucleotides, thereby preventing the formation of enzyme-substrate complexes, thereby preventing chain elongation, It can also inhibit DNA synthesis by binding deoxyribose fragments of DNA and preventing DNA polymerase from adding nucleotides to the growth chain. 3-Deaza-2 '-deoxyadenosine has antiviral activity[1][2].
[storage]

Store at -20°C
[References]

[1] Hendrickson CL, et al. Probing minor groove recognition contacts by DNA polymerases and reverse transcriptases using 3-deaza-2'-deoxyadenosine. Nucleic Acids Res. 2004 Apr 23;32(7):2241-50. DOI:10.1093/nar/gkh542
[2] Cristalli G, et al. Synthesis and biological evaluation of N6-cycloalkyl derivatives of 1-deazaadenine nucleosides: a new class of anti-human immunodeficiency virus agents. J Med Chem. 1995 Sep 29;38(20):4019-25. DOI:10.1021/jm00020a017
78582-17-9 suppliers list
Company Name: Antai Fine Chemical Technology Co.,Limited
Tel: 18503026267 , 18503026267
Website: www.chemicalbook.com/ShowSupplierProductsList1980510/0_EN.htm
Company Name: BOC Sciences
Tel: 16314854226; +16314854226 , +16314854226
Website: https://www.bocsci.com/
Company Name: NewCan Biotech Limited
Tel: +86-0571-86912261 +8613735419629 , +8613735419629
Website: https://www.newcanbio.com/
Company Name: Wuhu Nuowei chemistry Co., Ltd.
Tel: +86-0553-2911116-802 +86-18055311600 , +86-18055311600
Website: http://en.nuowei-chem.com/index.html
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207 , +8617767106207
Website: https://www.molcore.com/
Company Name: PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD
Tel: 0371-55159968 18137130222 , 18137130222
Website:
Company Name: Shenzhen Nexcon Pharmatechs Ltd.
Tel: +86-0755-89396905 +86-18025329037 , +86-18025329037
Website:
Company Name: Wuhu Nuowei Chemical Technology Co., Ltd  
Tel: 0553-8233716-803 18055311600
Website: www.nuowei-chem.com
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Wellman Pharmaceutical Group Limited  
Tel: 027-83778875 15807197853
Website: https://www.4008081911.com
Company Name: Shenzhen Regent Biochemical Technology Co., Ltd.  
Tel: 0755-85201366 18938635012
Website: http://www.regentsciences.com/
Company Name: Wuhu Huaren Science and Technology Co., Ltd.  
Tel: 0553-0553-5842013-801 18155347026
Website: https://www.huarensh.com
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774
Website: www.glpbio.cn
Company Name: Shanghai Minhan Pharmaceutical Technology Co., Ltd.  
Tel: 176121882
Website: http://www.suppliers.integle.com
Company Name: Shanghai meikai technology co., ltd  
Tel: 021-021-18721550-091-091 18721550091
Website: www.meikem.com
Company Name: MedBioPharmaceutical Technology Inc  
Tel: 021-69568360 18916172912
Website: http://www.med-bio.cn/
Company Name: NewCan Biotech Limited  
Tel: +86-0571-86912261 +86-15658003402
Website: https://www.newcanbio.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Tags:78582-17-9 Related Product Information

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.