| Identification | Back Directory | [Name]
1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE | [CAS]
78858-44-3 | [Synonyms]
2-O-METHYL PAF C-16
RZNRKXGAJMGLIM-RUZDIDTESA-N
1-hexadecyl-2-methoxyglycero-3-phosphocholine
1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE | [Molecular Formula]
C25H54NO6P | [MDL Number]
MFCD00065892 | [MOL File]
78858-44-3.mol | [Molecular Weight]
495.67 |
| Hazard Information | Back Directory | [Description]
2-O-methyl PAF C-16 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. Although the biological activities of 2-O-methyl PAF C-16 have not been well characterized, the C-18 analog has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart. In rat astrocytes, the C-18 analog causes the release of large quantities of NO by a pathway involving activation of NOS. |
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