| Identification | Back Directory | [Name]
AMI-408 | [CAS]
78866-14-5 | [Synonyms]
AMI-408
2-Naphthalenesulfonic acid, 7-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-[2-(4-methoxyphenyl)diazenyl]-, sodium salt (1:1) | [Molecular Formula]
C20H14Cl2N6O5S.Na | [MOL File]
78866-14-5.mol | [Molecular Weight]
544.32 |
| Hazard Information | Back Directory | [Uses]
AMI-408 is a PRMT1 inhibitor. AMI-408 can reduce H4R3me2as level in MLL-GAS7 leukemia cells[1]. | [IC 50]
PRMT1 | [References]
[1] Cheung N, et al. Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia. Cancer Cell. 2016 Jan 11;29(1):32-48. |
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