| Identification | Back Directory | [Name]
SNAP | [CAS]
79032-48-7 | [Synonyms]
SNAP
SNAP(D)
S-Nitroso-acetyl penicillamine
S-NITROSO-N-ACETYLPENICILLAMINE
N-ACETYL-3-(NITROSOTHIO)-D-VALINE
S-NITRO-N-ACETYL-D,L-PENACILLAMINE
N-Acetyl-S-nitroso-D-penicillaMine
S-nitroso-N-acetyl-D-penicillamine
S-Nitroso-N-acetyl-D-b,b-dimethylcysteine
S-NITROSO-N-ACETYL-D-BETA,BETA-DIMETHYLCYSTEINE
2-acetamido-3-methyl-3-(nitrosothio)butyric acid
2-acetamido-3-methyl-3-nitrososulfanylbutanoic acid
2-acetamido-3-methyl-3-nitrososulfanyl-butanoic acid
S-NITROSO-N-ACETYLPENICILLAMINE (SNAP) P OTENT VASODILATOR | [Molecular Formula]
C7H12N2O4S | [MDL Number]
MFCD00153852 | [MOL File]
79032-48-7.mol | [Molecular Weight]
220.25 |
| Hazard Information | Back Directory | [Chemical Properties]
Green Crystalline Solid | [Uses]
The D-isomer of SNAP. Serves as an NO donor | [Definition]
ChEBI: A nitroso compound that is N-acetyl-D-penicillamine in which the sulfanyl hydrogen is replaced by a nitroso group. | [Biological Activity]
A stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t ?of 37h. | [General Description]
Nitric oxide donor that begins to evolve nitric oxide immediately upon solubilization in aqueous buffers (t1/2 = 10 h). Mimics the actions of nitric oxide, including the relaxation of isolated bovine coronary artery rings (EC50 = 130 nM). Markedly activates soluble guanylate cyclase. Also reported to cause the reversible inactivation of protein kinase C activity. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg. | [Biochem/physiol Actions]
EC50 = 130 nM in relaxation of isolated bovine coronary artery rings | [storage]
Store at -20°C |
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| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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