| Identification | Back Directory | [Name]
biphenyl-4-yl[4-(2,5-dimethoxybenzyl)piperazin-1-yl]methanone | [CAS]
792928-94-0 | [Synonyms]
AMC-04
biphenyl-4-yl[4-(2,5-dimethoxybenzyl)piperazin-1-yl]methanone
Methanone, [1,1'-biphenyl]-4-yl[4-[(2,5-dimethoxyphenyl)methyl]-1-piperazinyl]- | [Molecular Formula]
C26H28N2O3 | [MOL File]
792928-94-0.mol | [Molecular Weight]
416.51 |
| Hazard Information | Back Directory | [Uses]
AMC-04 is an unfolded protein response (UPR) activator, which activates UPR pathway through ROS and p38 MAPK signaling and induces apoptotic cell death. AMC-04 can be used for cancer research[1]. | [References]
[1] Kim SY, et al. Molecular mechanisms underlying the effects of the small molecule AMC-04 on apoptosis: Roles of the activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway. Chem Biol Interact. 2020 Dec 1;332:109277. DOI:10.1016/j.cbi.2020.109277 |
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