| Identification | Back Directory | [Name]
PFKFB3-IN-2 | [CAS]
794552-84-4 | [Synonyms]
PFKFB3-IN-2
Benzoic acid, 4-[[(3-carboxyphenyl)sulfonyl]amino]-2-hydroxy- | [Molecular Formula]
C14H11NO7S | [MOL File]
794552-84-4.mol | [Molecular Weight]
337.3 |
| Chemical Properties | Back Directory | [Boiling point ]
633.0±65.0 °C(Predicted) | [density ]
1.669±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
2.85±0.10(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. PFKFB3-IN-2 has potential applications in cancer, neurodegenerative diseases, autoimmune diseases, inflammatory diseases, multiple sclerosis, metabolic diseases, angiogenesis inhibition and other diseases[1]. | [References]
[1] Fedichev P, et al. Pfkfb3 inhibitors and their uses. World Intellectual Property Organization. WO2020080979. |
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