| Identification | Back Directory | [Name]
glaucocalyxin A | [CAS]
79498-31-0 | [Synonyms]
LeukaMenin F
Wangzaozin B
Leucamenin F
glaucocalyxin A
Glaucocalyxin D
ent-7β,14α-Dihydroxy-16-kauren-3,15-dione
Kaur-16-ene-3,15-dione, 7,14-dihydroxy-, (7α,14R)- | [Molecular Formula]
C20H28O4 | [MDL Number]
MFCD31560787 | [MOL File]
79498-31-0.mol | [Molecular Weight]
332.437 |
| Chemical Properties | Back Directory | [Melting point ]
219.5-220.5℃ (ethyl ether ) | [Boiling point ]
513.4±50.0 °C(Predicted) | [density ]
1.22±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
13.15±0.70(Predicted) | [color ]
White | [InChI]
InChI=1/C20H28O4/c1-10-11-5-6-12-19(4)8-7-14(21)18(2,3)13(19)9-15(22)20(12,16(10)23)17(11)24/h11-13,15,17,22,24H,1,5-9H2,2-4H3/t11-,12-,13+,15+,17+,19-,20-/s3 | [InChIKey]
UCDVIBNDYLUWFP-WOOMQCEBNA-N | [SMILES]
[C@@]123C(=O)C(=C)[C@H](CC[C@@]1([H])[C@]1(C)CCC(=O)C(C)(C)[C@@]1([H])C[C@H]2O)[C@H]3O |&1:0,5,8,10,19,22,24,r| |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from the whole plant of Labiatae, Rabdosia japonica, Rubescens. | [Uses]
Glaucocalyxin A has the effect of anti-platelet aggregation and inhibits cancer cells. | [Biological Activity]
Glaucocalyxin A is an enantiomeric lauryl diterpene from Rabdosia japonica var. It inhibits the nuclear translocation of GLI1 by regulating the PI3K/Akt signaling pathway, thereby inducing apoptosis in osteosarcoma. Glaucocalyxin A has antitumor effect. | [IC 50]
PI3K | [storage]
Store at -20°C |
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| Company Name: |
WG reagent
|
| Telephone: |
13391486464 |
| Website: |
www.wgchemical.com |
|