| Identification | Back Directory | [Name]
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(4-morpholinyl)-4-oxo- | [CAS]
79660-59-6 | [Synonyms]
Antibacterial agent 19
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(4-morpholinyl)-4-oxo- | [Molecular Formula]
C16H16F2N2O4 | [MOL File]
79660-59-6.mol | [Molecular Weight]
338.31 |
| Chemical Properties | Back Directory | [Melting point ]
246-248 °C | [Boiling point ]
534.7±50.0 °C(Predicted) | [density ]
1.429±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
6.40±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Antibacterial agent 19 (compound 8) is a potent antibacterial agent. Antibacterial agent 19 has antibacterial activity against K. pneumoniae, (M-R)S. aureus and (M-R,V-R)S. aureus with MIC values of 0.022, 0.022 and 0.045 mg/mL, respectively[1]. | [References]
[1] Sunduru N, et, al. Synthesis and antibacterial evaluation of novel 8-fluoro Norfloxacin derivatives as potential probes for methicillin and vancomycin-resistant Staphylococcus aureus. Eur J Med Chem. 2011 Apr;46(4):1232-44. DOI:10.1016/j.ejmech.2011.01.044 |
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