| Identification | Back Directory | [Name]
SEPTIDE | [CAS]
79775-19-2 | [Synonyms]
SEPTIDE
PYR-FFPLM
[Glp6,L-Pro9]SP(6-11)
PYR-PHE-PHE-PRO-LEU-MET-NH2
GLP-PHE-PHE-PRO-LEU-MET-NH2
PGLU-PHE-PHE-PRO-LEU-MET-NH2
[GLP6,PRO9] SUBSTANCE P (6-11)
(PYR6,PRO9)-SUBSTANCE P (6-11)
[pGlu6,Pro9]subustance P(6-11)
[PGLU6, PRO9]SUBSTANCE P (6-11)
PYROGLU-PHE-PHE-PRO-LEU-MET NH2
(PYROGLU6, PRO8) SUBSTANCE P 6-11
SUBSTANCE P 6-11 (PYROGLU6, PRO9)
pGlu-L-Phe-L-Phe-L-Pro-L-Leu-L-Met-NH2
[Glp6,Pro9] Substance P (6-11)/Septide
[pGlu6, Pro9]-Substance P fragment 6-11
(Pyr6,Pro9)-Substance P (6-11), Septide
L-pGlu-L-Phe-L-Phe-L-Pro-L-Leu-L-Met-NH2
Substance P, fragment 6-11-inamide, [pGlu6, Pro9]
(Pyr 6,Pro9)-Substance P (6-11) Pyr-Phe-Phe-Pro-Leu-Met-NH2
5-OXO-L-PROLYL-L-PHENYLALANYL-L-PHENYLALANYL-L-PROLYL-LEUCYL-L- METHIONINAMIDE)
L-Methioninamide, 5-oxo-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-prolyl-L-leucyl-
(2S)-N-[(1S)-1-(benzyl)-2-[[(1S)-1-(benzyl)-2-[(2S)-2-[[(1S)-1-[[(1S)-1-carbamoyl-3-(methylthio)propyl]carbamoyl]-3-methyl-butyl]carbamoyl]pyrrolidin-1-yl]-2-keto-ethyl]amino]-2-keto-ethyl]-5-keto-pyrrolidine-2-carboxamide
(2S)-N-[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-5-oxopyrrolidine-2-carboxamide
(2S)-N-[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-azanyl-4-methylsulfanyl-1-oxo-butan-2-yl]amino]-4-methyl-1-oxo-pentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenyl-propan-2-yl]amino]-1-oxo-3-phenyl-propan-2-yl]-5-oxo-pyrrolidine-2-carboxamide | [Molecular Formula]
C39H53N7O7S | [MDL Number]
MFCD00076800 | [MOL File]
79775-19-2.mol | [Molecular Weight]
763.95 |
| Hazard Information | Back Directory | [Uses]
Septide ((Pyr6,Pro9)-Substance P) is a potent NK1 receptor agonist with a Kd value of 0.55 nM[1]. | [References]
[1] Hastrup H, Schwartz TW. Septide and neurokinin A are high-affinity ligands on the NK-1 receptor: evidence from homologous versus heterologous binding analysis. FEBS Lett. 1996 Dec 16;399(3):264-6. DOI:10.1016/s0014-5793(96)01337-3
[2] Pradier L, Mayaux JF, et al. Septide: an agonist for the NK1 receptor acting at a site distinct from substance P. Mol Pharmacol. 1994 Feb;45(2):287-93. PMID:7509440 |
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