| Identification | Back Directory | [Name]
1-[2-(2-chlorophenoxy)ethyl]-1H-indole-2,3-dione | [CAS]
797780-71-3 | [Synonyms]
1-[2-(2-chlorophenoxy)ethyl]-1H-indole-2,3-dione
1H-Indole-2,3-dione, 1-[2-(2-chlorophenoxy)ethyl]- | [Molecular Formula]
C16H12ClNO3 | [MOL File]
797780-71-3.mol | [Molecular Weight]
301.72 |
| Chemical Properties | Back Directory | [Boiling point ]
477.9±51.0 °C(Predicted) | [density ]
1.368±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
-2.60±0.20(Predicted) | [color ]
Orange to red |
| Hazard Information | Back Directory | [Uses]
DJ-1-IN-1 (compound 797780-71-3) is a DJ-1 inhibitor. DJ-1-IN-1 exhibits antiproliferative activity in ACHN cells with an IC50 value of 12.18 μM and can inhibit the Wnt signaling pathway. DJ-1-IN-1 can be used in cancer research[1]. | [IC 50]
DJ-1 | [References]
[1] Ma Y, et al. Discovery of novel covalent inhibitors of DJ-1 through hybrid virtual screening. Future Med Chem. 2024 Apr;16(7):665-677. DOI:10.4155/fmc-2023-0301 |
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Specs
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+31 15 251 8111 |
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OTAVA chemicals
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www.otavachemicals.com |
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