| Identification | Back Directory | [Name]
casuarictin | [CAS]
79786-00-8 | [Synonyms]
casuarictin
Galloyl pedunculagin
3,4,5-Trihydroxybenzoyl 2-O,3-O:4-O,6-O-bis[(4,4',5,5',6,6'-hexahydroxybiphenyl-2,2'-diyl)biscarbonyl]-β-D-glucopyranoside
(3,4,5-Trihydroxybenzoyl)2-O,3-O:4-O,6-O-bis[(4,4',5,5',6,6'-hexahydroxy-1,1'-biphenyl-2,2'-diyl)dicarbonyl]-β-D-glucopyranoside
2-O,3-O:4-O,6-O-Bis[(4,4',5,5',6,6'-hexahydroxy-1,1'-biphenyl-2,2'-diyl)biscarbonyl]-β-D-glucopyranose 1-(3,4,5-trihydroxybenzoate)
β-D-Glucopyranose, cyclic 2,3:4,6-bis[(1S)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1-(3,4,5-trihydroxybenzoate) | [Molecular Formula]
C41H28O26 | [MOL File]
79786-00-8.mol | [Molecular Weight]
936.65 |
| Chemical Properties | Back Directory | [Boiling point ]
1662.7±65.0 °C(Predicted) | [density ]
2.23±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
7.54±0.40(Predicted) | [color ]
Light brown to brown | [LogP]
4.700 (est) |
| Hazard Information | Back Directory | [Uses]
Casuarictin is a potent and competitive α-glucosidase inhibitor with an IC50 of 0.21 μg/mL. Casuarictin is a presenilin stabilization factor like protein (PSFL) protein inhibitor. Casuarictin can be used for Alzheimer's disease research[1]. | [Definition]
ChEBI:Casuarictin is a tannin. | [References]
[1] Yang Xu, et al. Identification of a novel α-glucosidase inhibitor from Melastoma dodecandrum Lour. fruits and its effect on regulating postprandial blood glucose. Food Chem. 2023 Jan 15:399:133999. DOI:10.1016/j.foodchem.2022.133999
[2] Rupali Kumari, et al. Casuarictin: A new herbal drug molecule for Alzheimer's disease as inhibitor of presenilin stabilization factor like protein. Heliyon. 2020 Nov 21;6(11):e05546. DOI:10.1016/j.heliyon.2020.e05546 |
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