| Identification | Back Directory | [Name]
5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile | [CAS]
80025-67-8 | [Synonyms]
Xanthine oxidase-IN-14
Xanthine dehydrogenase Inhibitor 1
5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile
1H-Pyrazole-4-carbonitrile, 5-amino-1-[4-(trifluoromethyl)phenyl]-
5-amino-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile, 10 mM in DMSO
5 amino 1 [4 (trifluoromethyl)phenyl] 1H pyrazole 4 carbonitrile,5amino1[4(trifluoromethyl)phenyl]1Hpyrazole4carbonitrile | [Molecular Formula]
C11H7F3N4 | [MDL Number]
MFCD11922351 | [MOL File]
80025-67-8.mol | [Molecular Weight]
252.2 |
| Hazard Information | Back Directory | [Uses]
Xanthine oxidase-IN-14 (Compound 3f) is an inhibitor for xanthine oxidase, with IC50 >100 μM. Xanthine oxidase-IN-14 inhibits proliferations of cancer cells MCF-7, NCI-H460 and SF-268, with IC50 greater than 150 μM[1]. | [References]
[1] Gupta S, et al., Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors. Eur J Med Chem. 2008 Apr;43(4):771-80. DOI:10.1016/j.ejmech.2007.06.002 |
|
| Company Name: |
Matrix Scientific
|
| Tel: |
803 788-9494 All other calls |
| Website: |
www.matrixscientific.com |
|