| Identification | Back Directory | [Name]
JP1302 | [CAS]
80259-18-3 | [Synonyms]
JP1302
MMV006172
Brn 5117597
JP 1302 dihydrochloride
N-(4-(4-Methyl-1-piperazinyl)phenyl)-9-acridinamine
9-Acridinamine, N-(4-(4-methyl-1-piperazinyl)phenyl)-
JP1302(9-Acridinamine, N-[4-(4-methyl-1-piperazinyl)phenyl]-)
N-[4-(4-Methyl-1-piperazinyl)phenyl]-9-acridinaminedihydrochloride | [Molecular Formula]
C24H24N4 | [MDL Number]
MFCD10565599 | [MOL File]
80259-18-3.mol | [Molecular Weight]
368.47 |
| Hazard Information | Back Directory | [Uses]
JP 1302 Dihydrochloride is an α2-adrenoceptor blocker and can be used for the treatment or prevention of nephropathy. | [Biological Activity]
α 2C -adrenoceptor antagonist that displays ~ 50-fold selectivity over other α 2 -adrenoceptor subtypes (K i values are 28, 1470, 1700 and 3150 nM for human α 2C , α 2B , α 2D and α 2A subtypes respectively). Potently antagonizes adrenalin-stimulated 35 GTP γ S binding in vitro (K B = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo . | [storage]
Desiccate at -20°C |
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