Identification | Back Directory | [Name]
Mafoprazine | [CAS]
80428-29-1 | [Synonyms]
Mafoprazine Mafoprazine Standard N-(4-{3-[4-(2-FLUOROPHENYL)PIPERAZIN-1-YL]PROPOXY}-3-METHOXYPHENYL)ACETAMIDE | [Molecular Formula]
C22H28FN3O3 | [MDL Number]
MFCD00868005 | [MOL File]
80428-29-1.mol | [Molecular Weight]
401.47 |
Chemical Properties | Back Directory | [Melting point ]
approximate 123℃ (dec.) | [Boiling point ]
590.5±50.0 °C(Predicted) | [density ]
1.192±0.06 g/cm3(Predicted) | [pka]
14.09±0.70(Predicted) | [InChI]
InChI=1S/C22H28FN3O3/c1-17(27)24-18-8-9-21(22(16-18)28-2)29-15-5-10-25-11-13-26(14-12-25)20-7-4-3-6-19(20)23/h3-4,6-9,16H,5,10-15H2,1-2H3,(H,24,27) | [InChIKey]
PHOCQBYGUQPMIB-UHFFFAOYSA-N | [SMILES]
C(NC1=CC=C(OCCCN2CCN(C3=CC=CC=C3F)CC2)C(OC)=C1)(=O)C |
Hazard Information | Back Directory | [Uses]
Mafoprazine is a phenylpiperazine derivative with variable affinities for neuronal receptors. It may exert its antipsychotic effects primarily through D2 receptor blockade and α-adrenergic activity, and may increase the activity of dopamine metabolites. | [References]
[1] Neurochemical study of mafoprazine, a new phenylpiperazine derivative |
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