| Identification | Back Directory | [Name]
alpha-tert-butyl-alpha-[(4-chlorophenoxy)methyl]-1H-1,2,4-triazol-1-ethanol | [CAS]
80456-55-9 | [Synonyms]
vibunazole
BAY-n-7133
alpha-tert-butyl-alpha-[(4-chlorophenoxy)methyl]-1H-1,2,4-triazol-1-ethanol
(2R)-1-(4-Chlorophenoxy)-3,3-dimethyl-2-(1,2,4-triazol-1-ylmethyl)butan-2-ol
α-[(4-Chlorophenoxy)methyl]-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol
1H-1,2,4-Triazole-1-ethanol, α-[(4-chlorophenoxy)methyl]-α-(1,1-dimethylethyl)- | [EINECS(EC#)]
279-475-3 | [Molecular Formula]
C15H20ClN3O2 | [MDL Number]
MFCD09838067 | [MOL File]
80456-55-9.mol | [Molecular Weight]
309.791 |
| Chemical Properties | Back Directory | [Boiling point ]
486.3±55.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
12.85±0.29(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Vibunazole is used as an antifungal agent. | [in vivo]
The untreated, infected mice lost weight initially and progressively, whereas treated mice gain weight after an initial loss with Vibunazole (all doses), BAY 1 9139 and ketoconazole at 2.5 mg/kg/day. With both Vibunazole and BAY 1 9139, the 5 and 10 mg/kg doses yield serum concentrations exceeding the MICs for the Coccidioides immitis test strain (0.8 and 1.5 μg/mL respectively) for periods in excess of 30 min after injection[1]. | [storage]
Store at -20°C |
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