Identification | Back Directory | [Name]
ACTINOMYCIN C | [CAS]
8052-16-2 | [Synonyms]
hbf386 nsc-18268 sanamicia sanamycin CACTINOMYCIN actinochrysin ACTINOMYCIN C Actinochrysin C ACTINOMYCIN C USP/EP/BP ACTINOMYCIN C FROM STREPTOMYCES & ACTINOMYCIN C, STREPTOMYCES CHRYSOMALLUS mixtureofdactinomycin(10%),actinomycinc2(45%),andactinomycinc3(45%) | [EINECS(EC#)]
232-485-1 | [MDL Number]
MFCD00070921 |
Chemical Properties | Back Directory | [Melting point ]
252° | [alpha ]
D25 -325 to -349° (c = 0.25 in ethanol) | [Boiling point ]
848.87°C (rough estimate) | [density ]
1.0721 (rough estimate) | [refractive index ]
1.6000 (estimate) | [storage temp. ]
2-8°C | [Merck ]
13,1606 |
Hazard Information | Back Directory | [Uses]
Actinomycin C is an antibiotic produced by?Streptomyces chrysomallus that intercalates DNA. | [Uses]
Antineoplastic. | [Purification Methods]
(A commercial mixture of Actinomycin C1 5%, C2 30% and C3 65% is available). Actinomycin C1 (native) crystallises from EtOAc as red crystals, is soluble in CHCl3, *C6H6 and Me2CO, and has m 246-247o(dec), [] 20D -328o (0.22, MeOH) and max 443nm ( 25,000) and 240nm ( 34,000). Actinomycin C2 (native) crystallises as red needles from EtOAc and has m 244-246o(dec), [] D -325o (c 0.2, MeOH), max 443nm ( 25,300) and 240nm ( 33,400). Actinomycin C3 (native) recrystallises from cyclohexane, or *C6H6/MeOH/cyclohexane as red needles with m 238-241o (dec), [] D -321o (c 0.2, MeOH), max 443nm ( 25,000) and 240nm ( 33,300). [Brockman & Lackner, Chem Ber 101 1312 1968.] Itis light sensitive.[Beilstein 27 III/IV 9642.] |
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Company Name: |
SIGMA-RBI
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800 736 3690 (Orders) |
Website: |
www.sigma-aldrich.com |
Company Name: |
DeBioChem
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025-84715147 |
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www.chemicalbook.com/ShowSupplierProductsList10203/0_EN.htm |
Company Name: |
Alexis Corporation
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Tel: |
+41 61 926 8989 |
Website: |
www.alexis-biochemicals.com |
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