| Identification | Back Directory | [Name]
N2-Isobutyryl-2'-Fluoro-2'-deoxyguanosine | [CAS]
80681-25-0 | [Synonyms]
iBu-2'-F-dG
N2-ibu-2'-F-dG
2'-Deoxy-2'-fluoro-N-isobutyrylguanosine
N2-Isobutyryl-2'-Fluoro-2'-deoxyguanosine
2'-Deoxy-N2-isobutyryl-2'-fluoroguanosine
N2-isobutyryl-2'-deoxy-2'-fluoroguanosine
2'-deoxy-N2-isobutyryl-2'-fluoro-2'-deoxyguanosine
2'-Deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)guanosine
Guanosine, 2'-deoxy-2'-fluoro-N-(2-Methyl-1-oxopropyl)-
N-[9-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
N-(9-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide | [Molecular Formula]
C14H18FN5O5 | [MDL Number]
MFCD15145246 | [MOL File]
80681-25-0.mol | [Molecular Weight]
355.32 |
| Chemical Properties | Back Directory | [density ]
1.78±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
9.16±0.20(Predicted) | [InChIKey]
SLHADUUWJSVYGQ-HTFXMJNNSA-N | [SMILES]
OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](F)[C@@H]1O |
| Hazard Information | Back Directory | [Uses]
2'-F-iBu-G (2′-Deoxy-2′-fluoro-N-isobutyrylguanosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides[1]. | [References]
[1] Kawasaki AM, et al. Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets. J Med Chem. 1993 Apr 2;36(7):831-41. DOI:10.1021/jm00059a007 |
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