| Identification | Back Directory | [Name]
MQCKXANXFRGFND-CGIARSFXSA-N | [CAS]
810668-53-2 | [Synonyms]
Resolvin D2 methyl ester
MQCKXANXFRGFND-CGIARSFXSA-N
4,8,10,12,14,19-Docosahexaenoic acid, 7,16,17-trihydroxy-, methyl ester, (4Z,7S,8E,10Z,12E,14E,16R,17S,19Z)- | [Molecular Formula]
C23 H34 O5 | [MOL File]
810668-53-2.mol | [Molecular Weight]
390.51 |
| Chemical Properties | Back Directory | [Boiling point ]
562.1±50.0 °C(Predicted) | [density ]
1.064±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.05 mg/ml | [pka]
13.38±0.20(Predicted) |
| Hazard Information | Back Directory | [Description]
Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. It evokes diverse anti-inflammatory effects which may mediate the resolution of inflammation. RvD2 methyl ester is a methyl ester version of the free acid which may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid. | [Uses]
Resolvin D2 Methyl Ester acts as a lipophilic prodrug form while in the free acid state which alters its distribution and pharmacokinetic properties. |
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