| Identification | Back Directory | [Name]
ACETYLLOVASTATIN | [CAS]
81189-92-6 | [Synonyms]
ACETYLLOVASTATIN
Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-(acetyloxy)tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, (2S)- | [Molecular Formula]
C26H38O6 | [MDL Number]
MFCD09038917 | [MOL File]
81189-92-6.mol | [Molecular Weight]
446.58 |
| Chemical Properties | Back Directory | [Boiling point ]
568.9±50.0 °C(Predicted) | [density ]
1.12±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: ≥ 250 mg/mL (559.81 mM) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines[1]. | [References]
[1] Cazar, et al. Antimicrobial Butyrolactone I Derivatives from the Ecuadorian Soil Fungus Aspergillus terreus Thorn. var terreus. World Journal of Microbiology and Biotechnology, 2005,21(6-7), 1067–1075. |
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