ChemicalBook--->CAS DataBase List--->81608-29-9

81608-29-9

81608-29-9 Structure

81608-29-9 Structure
IdentificationBack Directory
[Name]

gastrin releasing peptide (14-27)
[CAS]

81608-29-9
[Synonyms]

Grp (14-27)
C-Terminal peptide bombesin
14-27-Porcine gastrin-releasing peptide
Bombesin, 1-L-methionine-2-L-tyrosine-3-L-proline-4-L-arginine-7-L-histidine-, (2S-(2alpha,5alpha,6beta(S*)))-
L-Methioninamide, L-methionyl-L-tyrosyl-L-prolyl-L-arginylglycyl-L-asparaginyl-L-histidyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-
[Molecular Formula]

C75H110N24O16S2
[MOL File]

81608-29-9.mol
[Molecular Weight]

1667.96
Chemical PropertiesBack Directory
[density ]

1.49±0.1 g/cm3(Predicted)
[pka]

9.84±0.15(Predicted)
[Sequence]

Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2
Hazard InformationBack Directory
[Uses]

GRP (14-27) (human, porcine, canine) is a bombesin receptor ligand. The specific binding of GRP (14-27) is inhibited by GTP and GDP, whereas GMP was without effect[1].
[References]

[1] J B Fischer, et al. The bombesin receptor is coupled to a guanine nucleotide-binding protein which is insensitive to pertussis and cholera toxins. J Biol Chem. 1988 Feb 25;263(6):2808-16. PMID:2830264
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