| Identification | Back Directory | [Name]
1-[3-[3,5-bis(trifluoromethyl)phenyl]-2-propynyl]-4-(tert-butyl)piperidinium chloride | [CAS]
81613-60-7 | [Synonyms]
Flupropadine Hydrochloride
NLECRQYFKWPVEQ-UHFFFAOYSA-N
1-[3-[3,5-bis(trifluoromethyl)phenyl]-2-propynyl]-4-(tert-butyl)piperidinium chloride | [EINECS(EC#)]
279-786-4 | [Molecular Formula]
C20H24ClF6N | [MOL File]
81613-60-7.mol | [Molecular Weight]
427.855 |
| Hazard Information | Back Directory | [Uses]
Flupropadine is a sub-acute rodenticide. | [Production Methods]
The industrial scale manufacturing of flupropadine is not described in open literature, but its structure and the limited synthetic information available indicate that commercial production followed a straightforward modular assembly of three components: (1) synthesis of the tert butylpiperidine ring, (2) preparation of the bis(trifluoromethyl)phenyl substituted propargyl intermediate, and (3) N alkylation of the piperidine with the propargyl side chain to form the final tertiary amine. A key step involved coupling the substituted propargyl fragment with the tert butylpiperidine core, consistent with standard late 20th century amine alkylation processes used for lipophilic rodenticides. The hydrochloride salt would then be produced by acid–base quenching of purified flupropadine with anhydrous hydrogen chloride in an organic solvent, followed by crystallisation and drying to yield the stable, isolable salt. | [Mechanism of action]
Chronic, cumulative anticoagulant | [Pesticide Type]
Rodenticide |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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