| Identification | Back Directory | [Name]
m-PEG5-nitrile | [CAS]
81836-41-1 | [Synonyms]
m-PEG5-nitrile
4,7,10,13,16-Pentaoxaheptadecanenitrile | [Molecular Formula]
C12H23NO5 | [MDL Number]
MFCD31615439 | [MOL File]
81836-41-1.mol | [Molecular Weight]
261.31 |
| Hazard Information | Back Directory | [Description]
m-PEG5-nitrile is a PEG linker containing a nitrile terminal group. The nitrile group can undergo hydrolysis, reduction and other reactions. The hydrophilic PEG spacer increases the solubility of compounds in aqueous media. | [Uses]
m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | [References]
[1] Saifer MG, et al. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46. DOI:10.1016/j.molimm.2013.07.014 |
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